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cgrp receptor antagonists  (Boehringer Ingelheim)

 
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    Boehringer Ingelheim cgrp receptor antagonists
    Cgrp Receptor Antagonists, supplied by Boehringer Ingelheim, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/cgrp+receptor+antagonists/antagonists+cgrp+receptor/pm41357877-188-10-2
    Average 86 stars, based on 1 article reviews
    cgrp receptor antagonists - by Bioz Stars, 2026-11
    86/100 stars

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    Related Articles

    Biomarker Discovery:

    Article Title: Neuropeptides 2010 Conference: The 7th Joint Meeting of the European Neuropeptide Club and the American Summer Neuropeptide Conference 21–24 June 2010 Pécs, Hungary
    Article Snippet: Contents lists available at ScienceDirect Neuropeptides journal homepage: www.elsevier .com/locate /npep Neuropeptides 2010 Conference: The 7th Joint Meeting of the European Neuropeptide Club and the American Summer Neuropeptide Conference 21–24 June 2010 Pécs, Hungary doi:10.1016/j.npep.2010.07.001



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    Image Search Results


    CGRP Promotes Angiogenesis in HUVECs and Pulp Repair via Upregulation of CD31/VEGFA (A) Representative images of tube formation assays using HUVECs treated with or without CGRP. Scale bar, 500 µm. (n = 3, *p < 0.05, **p < 0.01 vs. NC group). (B) ​ Representative images of scratch wound healing assays of HUVECs at 0,12 and 24 h post-CGRP treatment and quantitative analysis of wound closure rate. Scale bar, 100 µm. (n = 3, *p < 0.05 vs. NC group). (C) ​ qRT-PCR and Western blot analysis of CD31 and VEGFA levels in HUVECs. (n = 3, **p < 0.01, ***p < 0.001 vs. NC group). (D) ​ Representative immunofluorescence images showing CD31 + blood vessels (red) in the injured pulp region of mice treated with either vehicle (NC) or the CGRP receptor antagonist BIBN4096BS. Nuclei are counterstained with DAPI (blue). Scale bar, 50 µm. Green dashed line, dentin injury (cavity). Green arrow, region of interest (ROI) in the pulp horn beneath the injury site, where vascular changes were analyzed. (E) ​ CGRP-activated endothelial cells promote the mineralization of DPSCs via a paracrine mechanism. (n = 3, **p < 0.01vs. NC group).

    Journal: Frontiers in Cell and Developmental Biology

    Article Title: CGRP-mediated neuro-vascular-pulp cell crosstalk is essential for dental pulp repair

    doi: 10.3389/fcell.2026.1793692

    Figure Lengend Snippet: CGRP Promotes Angiogenesis in HUVECs and Pulp Repair via Upregulation of CD31/VEGFA (A) Representative images of tube formation assays using HUVECs treated with or without CGRP. Scale bar, 500 µm. (n = 3, *p < 0.05, **p < 0.01 vs. NC group). (B) ​ Representative images of scratch wound healing assays of HUVECs at 0,12 and 24 h post-CGRP treatment and quantitative analysis of wound closure rate. Scale bar, 100 µm. (n = 3, *p < 0.05 vs. NC group). (C) ​ qRT-PCR and Western blot analysis of CD31 and VEGFA levels in HUVECs. (n = 3, **p < 0.01, ***p < 0.001 vs. NC group). (D) ​ Representative immunofluorescence images showing CD31 + blood vessels (red) in the injured pulp region of mice treated with either vehicle (NC) or the CGRP receptor antagonist BIBN4096BS. Nuclei are counterstained with DAPI (blue). Scale bar, 50 µm. Green dashed line, dentin injury (cavity). Green arrow, region of interest (ROI) in the pulp horn beneath the injury site, where vascular changes were analyzed. (E) ​ CGRP-activated endothelial cells promote the mineralization of DPSCs via a paracrine mechanism. (n = 3, **p < 0.01vs. NC group).

    Article Snippet: The CGRP receptor antagonist BIBN4096BS was purchased from Shanghai Haoyuan Chemexpress Co. (Shanghai, China).

    Techniques: Quantitative RT-PCR, Western Blot, Immunofluorescence